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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAE1
All Species:
38.79
Human Site:
S459
Identified Species:
65.64
UniProt:
Q13564
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13564
NP_001018169.1
534
60246
S459
E
D
I
G
K
L
K
S
C
L
T
G
F
L
Q
Chimpanzee
Pan troglodytes
XP_001159531
534
60179
S459
E
D
I
G
K
L
K
S
C
L
T
G
F
L
Q
Rhesus Macaque
Macaca mulatta
XP_001085059
534
60247
S459
E
D
I
G
K
L
K
S
C
L
T
G
F
L
Q
Dog
Lupus familis
XP_852003
534
60357
S459
E
D
I
G
K
L
K
S
C
L
T
G
F
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBW6
534
60255
S459
E
D
I
G
K
L
K
S
C
L
T
G
F
L
Q
Rat
Rattus norvegicus
Q9Z1A5
534
60364
S459
E
D
I
G
K
L
K
S
C
L
T
G
F
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505632
525
59197
S450
E
D
I
G
K
L
K
S
C
L
I
G
F
L
Q
Chicken
Gallus gallus
Q5ZIE6
535
60465
S460
D
D
I
G
K
L
K
S
C
L
T
S
F
L
Q
Frog
Xenopus laevis
Q6NTW6
533
60607
S458
S
D
I
G
K
L
K
S
C
L
N
G
L
L
Q
Zebra Danio
Brachydanio rerio
Q7SXP2
533
60386
L458
E
D
I
N
K
L
K
L
C
V
N
S
L
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTE9
524
58698
S449
Q
D
I
G
R
L
K
S
I
A
A
K
M
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18217
541
60764
E466
R
V
E
V
L
I
R
E
A
L
K
D
E
Q
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42744
540
60016
T465
D
I
S
R
L
K
T
T
A
L
S
L
L
T
D
Baker's Yeast
Sacchar. cerevisiae
Q12059
462
52834
L391
S
N
A
L
L
D
A
L
V
M
V
Q
F
W
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.7
N.A.
97
96.8
N.A.
82.7
83.9
78.8
73
N.A.
45.1
N.A.
37.7
N.A.
Protein Similarity:
100
99.6
99.4
98.8
N.A.
98.6
98.3
N.A.
91.1
93
89.6
85.9
N.A.
64.2
N.A.
55.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
80
60
N.A.
46.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
80
66.6
N.A.
60
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
25.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.7
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
15
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% C
% Asp:
15
79
0
0
0
8
0
0
0
0
0
8
0
0
15
% D
% Glu:
58
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
65
0
0
% F
% Gly:
0
0
0
72
0
0
0
0
0
0
0
58
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
79
0
0
8
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
72
8
79
0
0
0
8
8
0
0
0
% K
% Leu:
0
0
0
8
22
79
0
15
0
79
0
8
22
79
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
72
% Q
% Arg:
8
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
8
0
0
0
0
72
0
0
8
15
0
0
8
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
50
0
0
8
0
% T
% Val:
0
8
0
8
0
0
0
0
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _